Matcha and Anxiety: Caffeine Sensitivity, Jitters, and Individual Response
Author: Ukrainian Psychological Hub · Published: September 28, 2026 · Editorial Policy
Matcha can make some people feel anxious or jittery because it contains caffeine. The effect is not universal, and it is not determined by the word “matcha” alone. What matters is the caffeine dose in the powder you use, your sensitivity to caffeine, your recent sleep and caffeine intake, other stimulant sources, medications and health factors that affect caffeine handling, and the way you interpret the physical sensations of arousal.
For most people, the useful question is therefore not “Is matcha good or bad for anxiety?” but “What happens to me at this matcha dose, at this time of day, under these conditions?” Matcha also contains L-theanine and other tea compounds, but current evidence does not support the popular claim that L-theanine reliably cancels caffeine-induced anxiety or makes every serving of matcha “calm caffeine.”
This article focuses specifically on matcha and anxiety: caffeine sensitivity, jitters, anxious arousal, individual response, the limits of L-theanine claims, and practical ways to test whether matcha is contributing to how you feel. For the broader beverage context, see our guide to tea types, caffeine, brewing, taste, and psychology.
Matcha and anxiety: the short answer
Yes, matcha can worsen anxious feelings in a caffeine-sensitive person. Caffeine can increase physiological arousal, and higher caffeine exposure is associated with a greater likelihood of anxiety symptoms on average. A 2026 systematic review of 27 studies concluded that the evidence predominantly supports a dose-dependent increase in anxiety symptoms after caffeine, while also finding meaningful differences according to habitual caffeine use and other individual factors. Nascimento and colleagues’ systematic review
At the same time, matcha does not automatically cause anxiety. A person who tolerates a given caffeine dose may experience alertness without distress, and even people with panic disorder did not show an increase in subjective anxiety after 150 mg of caffeine in one 2025 randomized crossover trial, although caffeine increased physiological arousal and avoidance behavior. Hoppe and colleagues’ 150 mg caffeine trial
Matcha is also not an established treatment for anxiety disorders. A small matcha-specific trial reported lower anxiety during a stressful training period with one carefully characterized matcha product, but that study involved 39 students, a specific formulation and context, and ordinary stress-related anxiety rather than treatment of a diagnosed anxiety disorder. Unno and colleagues’ matcha trial
The most defensible conclusion is simple: matcha can feel calming, neutral, stimulating, or unpleasantly activating depending on the person and the dose. The caffeine effect is established; a universal anti-anxiety effect from matcha is not.
How much caffeine is in matcha?
Matcha is powdered green tea, so the leaf material is consumed rather than steeped and discarded. That makes the amount of powder an especially important part of the dose. There is no single caffeine number for “one matcha,” because powder composition and serving size vary.
In a laboratory analysis of commercially available green teas, the matcha products contained roughly 17.7 to 35.0 mg of caffeine per gram of powder. At those measured concentrations, 2 g of powder would contain about 35 to 70 mg of caffeine. The study also found variation among products, including within culinary and ceremonial labels. Meyer and colleagues’ commercial tea analysis
Clinical matcha studies illustrate the same point. One 2024 trial used 2.7 g of matcha containing 71.5 mg of caffeine, while another long-term trial used 2 g containing 66.2 mg. These are examples from particular research products, not universal serving values. Baba and colleagues’ 2024 matcha trial For the 2 g formulation, see Uchida and colleagues’ 12-month matcha trial.
This is why a heaping scoop, a café drink made with several grams of powder, and a lightly prepared home matcha can produce very different stimulant exposure even though all three are called matcha. Adding more water changes concentration and taste; it does not remove caffeine already present in the powder.
“Ceremonial grade” does not tell you your caffeine dose
Retail grade language is not a standardized caffeine label. In the commercial analysis above, ceremonial products averaged more caffeine per gram than culinary products, but the sample was small and the finding should not be turned into a rule that every ceremonial matcha is more caffeinated. If caffeine sensitivity matters to you, grams of powder and product-specific information are more useful than a marketing grade.
Why matcha can feel like anxiety
Caffeine increases arousal by blocking adenosine signaling
At concentrations reached during ordinary consumption, caffeine’s best-established central mechanism is antagonism of adenosine receptors. Adenosine participates in the regulation of neural activity and sleep pressure; blocking its receptors shifts the system toward wakefulness and arousal. Fredholm’s review of caffeine and adenosine receptors
That arousal can be useful. It can feel like greater alertness, energy, readiness, or concentration. When the same activation is stronger than a person wants or expects, it can be experienced as restlessness, shakiness, tension, an uncomfortable awareness of heartbeat, difficulty relaxing, or a sense of being “wired.” The U.S. Food and Drug Administration lists anxiety, jitters, increased heart rate, palpitations, insomnia, upset stomach, nausea, and headache among possible signs of too much caffeine for an individual. FDA caffeine guidance
Jitters and anxiety overlap, but they are not identical
Jitters are a colloquial description of stimulant-type bodily activation: trembling, internal shakiness, restlessness, or feeling overactivated. Anxiety includes emotional and cognitive components as well as bodily arousal. The two can overlap strongly, especially when a fast heartbeat, tremor, or agitation is interpreted as threatening.
A temporary stimulant response after matcha does not by itself establish an anxiety disorder. It is more precise to say that caffeine may produce or amplify sensations that resemble parts of an anxiety response. If symptoms are new, severe, persistent, or unusual, they should not automatically be attributed to matcha.
What the evidence says about caffeine and anxiety
The strongest evidence relevant to matcha anxiety comes from caffeine research rather than from matcha-specific clinical trials. A 2024 meta-analysis of eight articles involving 546 healthy participants found that caffeine increased anxiety and that larger doses produced larger effects on average. Liu and colleagues’ caffeine-anxiety meta-analysis
The newer 2026 systematic review reached a similar overall conclusion while emphasizing variation by habitual caffeine use. These reviews support a dose-response relationship at the population level, but they do not provide a universal personal threshold. Someone may dislike 50 or 70 mg, while another person may tolerate much more without feeling anxious.
Population safety guidance answers a different question from personal anxiety sensitivity. The FDA cites 400 mg per day for most adults as an amount not generally associated with negative effects, while explicitly noting that sensitivity varies. The European Food Safety Authority similarly reports that single doses up to 200 mg and total daily intake up to 400 mg do not raise safety concerns for healthy adults in the general population, while noting that even 100 mg near bedtime may affect sleep in some adults. EFSA caffeine guidance
Those numbers are safety reference points, not goals and not anxiety thresholds. A person can experience jitters or anxious arousal well below 400 mg.
What about panic attacks?
High-dose caffeine challenge studies have shown a much stronger panic response in people with panic disorder than in healthy controls. A 2022 systematic review and meta-analysis found marked vulnerability in panic disorder, but the classic challenge studies generally used approximately 400 to 750 mg of caffeine. Klevebrant and Frick’s panic-disorder meta-analysis
That dose range is crucial. It is far above the caffeine content of many ordinary matcha servings, so those challenge results should not be used to claim that a standard bowl of matcha routinely causes panic attacks. The 2025 150 mg trial is a useful counterpoint: it did not increase subjective anxiety at rest in the studied panic-disorder group, although it did increase some measures of arousal and avoidance. The practical lesson is individual assessment, not a blanket rule.
What the evidence says about matcha itself
Matcha-specific evidence on anxiety is much thinner than the caffeine literature. The best-known human study is the 2018 trial by Unno and colleagues. Thirty-nine pharmacy students consumed 3 g per day of either a test matcha or a comparison matcha before and during a stressful pharmacy-practice period. State anxiety and a salivary stress marker were lower in the test-matcha group under the study conditions.
The result is interesting, but it is preliminary. The study did not test matcha as treatment for generalized anxiety disorder, panic disorder, social anxiety disorder, or another clinical condition. It tested a small group during a particular real-world stressor, and the authors’ hypothesis depended on the balance among several compounds in the specific matcha products. The result cannot be generalized to every matcha on the market.
A 2017 randomized intervention study using 4 g of matcha found small effects on some attention and memory measures but no significant overall mood change on the Profile of Mood States. Dietz and colleagues’ matcha intervention study
Together, the matcha trials support continued research on stress, attention, and mood. They do not establish matcha as an anti-anxiety treatment.
Does L-theanine in matcha cancel out caffeine?
No reliable evidence supports the claim that L-theanine simply “cancels” caffeine. L-theanine is a tea amino acid with genuine research interest, but the effects of isolated L-theanine, L-theanine plus caffeine, whole tea, and matcha should be kept separate.
A 2026 systematic review and meta-analysis of 31 randomized trials involving 1,168 participants found a robust short-term effect of a 200 mg L-theanine dose on one attention outcome, while the reduction in acute stress was modest and strongly influenced by studies at high risk of bias. Anxiety effects were inconsistent and generally not significant. Gerolymos and colleagues’ 2026 L-theanine meta-analysis
A 2025 systematic review and meta-analysis of randomized trials of tea, L-theanine, and L-theanine plus caffeine found small-to-moderate differences favoring some cognitive and mood outcomes, but confidence intervals often showed substantial uncertainty. Importantly, the authors called for more studies using actual tea beverages or tea-equivalent doses in free-living participants. Payne and colleagues’ tea and L-theanine review
This matters because supplement trials may use 200 mg or 400 mg of isolated L-theanine, whereas a matcha serving can contain a much smaller and highly variable amount. Evidence from an isolated compound cannot be copied directly onto a cup of matcha.
So if a matcha serving makes you jittery, the presence of L-theanine does not invalidate your experience and does not guarantee that increasing L-theanine through a supplement will solve it. The most direct variable to examine first is usually the caffeine exposure itself.
Why matcha may feel calmer than coffee for some people
Many people report that matcha feels smoother than coffee. That experience can be real without requiring a single universal biochemical explanation.
The caffeine dose may simply be lower
A common matcha serving can contain less caffeine than a large coffee, although either beverage can vary widely. If someone feels better after 50 to 70 mg from matcha than after 150 to 250 mg from coffee, the difference may be explained largely by dose. For a direct comparison of the anxiety side of coffee, see Coffee and Anxiety: Why Caffeine Can Make Some People Feel More Anxious.
The beverage context can change the experience
Taste, temperature, preparation, pacing, and ritual can shape attention and expectation. Preparing matcha may function as a deliberate pause; drinking it in a quiet setting can create a different psychological context from rapidly consuming a large takeaway coffee during a stressful commute. That does not neutralize pharmacology. It changes the situation in which the pharmacology is experienced.
Expectation can influence subjective caffeine effects
Balanced-placebo research shows that beliefs about caffeine can alter some subjective ratings and perceived effects independently of the active drug. Lotshaw and colleagues’ balanced-placebo study
This is one reason “matcha gives calm focus” can become partly self-reinforcing as an expectation. Expectancy effects do not mean symptoms are imaginary. A person can have a real pharmacological caffeine response and a real expectation-driven interpretation at the same time.
Direct head-to-head evidence showing that matcha produces less anxiety than coffee at matched caffeine doses is limited. Claims that matcha is universally anxiety-safe because of L-theanine go beyond the evidence.
Why individual response to matcha varies
Caffeine metabolism is highly variable
Caffeine is metabolized primarily in the liver, and its pharmacokinetics vary substantially between people. A systematic analysis drawing on 141 publications documented large interindividual variability and examined factors including smoking, oral contraceptive use, drug interactions, and disease. Grzegorzewski and colleagues’ systematic caffeine pharmacokinetics analysis
A major pharmacology review likewise describes variation related to CYP1A2 activity, hormones, age, smoking, diet, medications, and genetic differences affecting both caffeine metabolism and caffeine response. Nehlig’s review of individual differences in caffeine
This helps explain why the same measured dose can feel mild to one person and excessive to another.
Habitual caffeine use changes the comparison
Someone who routinely consumes caffeine may respond differently from someone who rarely uses it. Tolerance can reduce some familiar stimulant effects, while a sudden reduction in habitual caffeine can produce withdrawal symptoms such as headache, fatigue, irritability, or difficulty concentrating. The FDA therefore recommends reducing caffeine gradually if you want to cut back. FDA guidance on reducing caffeine
Sleep can turn yesterday’s matcha into today’s vulnerability
Caffeine can disrupt sleep, and poor sleep can make the next day feel more emotionally reactive or physically uncomfortable. A 2023 systematic review and meta-analysis of 24 studies found that caffeine reduced total sleep time and sleep efficiency and increased sleep-onset latency on average. Gardiner and colleagues’ caffeine-and-sleep meta-analysis
The exact timing at which caffeine becomes sleep-disruptive depends on dose and the person. This creates a possible loop: afternoon matcha disturbs sleep, worse sleep increases next-day vulnerability to anxious arousal, and more caffeine is then used to compensate for tiredness.
Stress, other stimulants, and total daily caffeine matter
Matcha does not arrive in an empty nervous system. A serving taken after poor sleep, during intense stress, on top of coffee, energy drinks, cola, pre-workout products, caffeine tablets, or some medications can feel very different from the same serving on a rested day without other stimulants. Total exposure matters more than the identity of the last drink.
How to tell whether matcha is contributing to your anxiety or jitters
A single unpleasant episode can suggest a connection, but a repeatable pattern is more informative. The simplest useful test is a structured personal comparison rather than a guess.
Track the actual matcha dose
Measure the powder in grams for several servings instead of relying on a scoop whose size changes. Note the product, amount of powder, time consumed, and whether the drink was one serving or a café preparation with multiple scoops.
Count the rest of your caffeine
Record coffee, tea, energy drinks, cola, chocolate, pre-workout products, caffeine medications, and supplements consumed that day. If symptoms follow “matcha” only on days when total caffeine is high, the relevant variable may be cumulative exposure rather than matcha itself.
Look at timing
Notice when symptoms start relative to the drink and whether late-day matcha is associated with worse sleep. A consistent sequence — matcha, then unwanted stimulation, then improvement when the dose is reduced — is more informative than a general belief that matcha is either calming or anxiety-producing.
Change one variable at a time
If it is safe and practical for you, compare your usual serving with a smaller measured serving on otherwise similar days. Changing powder amount, coffee intake, sleep schedule, food, supplements, and exercise all at once makes the result harder to interpret.
This kind of self-observation can identify a personal pattern. It does not diagnose an anxiety disorder or rule out another cause of palpitations, tremor, dizziness, or other symptoms.
What to do if matcha makes you anxious or jittery
The most direct intervention is to reduce stimulant exposure rather than trying to “balance” it with another supplement.
Use less matcha powder
Because caffeine dose tracks the amount and composition of powder, reducing the grams of matcha is a direct way to lower exposure. More water can soften taste and concentration, but only less powder lowers the caffeine present in that serving.
Avoid stacking caffeine sources
If you already had coffee, an energy drink, pre-workout, or another caffeinated tea, a matcha later in the day may push total exposure past your comfortable range. The live English Hub guide to caffeine and anxiety explains the broader dose-and-sensitivity relationship.
Move matcha earlier if sleep is part of the problem
If matcha reliably delays sleep or makes sleep lighter, earlier timing or a lower dose is more evidence-based than assuming the evening ritual is harmless because matcha contains L-theanine.
Reduce gradually if your total caffeine intake is high
Abrupt caffeine reduction can produce withdrawal symptoms in habitual users. A gradual reduction is often easier to interpret and tolerate.
Do not use matcha as self-treatment for a clinical anxiety disorder
Enjoying matcha can be part of an ordinary routine, and reducing caffeine may help a person whose symptoms are caffeine-sensitive. That is different from treating generalized anxiety disorder, panic disorder, social anxiety disorder, or another clinical condition. Matcha is not an established treatment for those disorders.
Matcha, panic attacks, and clinical anxiety
A panic attack is not the same thing as ordinary caffeine jitters. Caffeine can create sensations that overlap with panic — a pounding heart, shakiness, restlessness, or a sudden feeling of activation — and high-dose caffeine challenge studies show heightened vulnerability in panic disorder. Yet the doses in those studies are often far above those in ordinary matcha.
If you already have an anxiety disorder, the useful question is still individual: what caffeine dose do you tolerate, and what does your clinician recommend in the context of your symptoms, medications, sleep, and health? A diagnosis does not automatically mean every caffeinated drink will cause symptoms, and a comfortable experience with matcha does not mean caffeine cannot affect someone else.
If you develop severe or unusual symptoms such as chest pain, fainting, severe shortness of breath, or symptoms that feel medically urgent, seek urgent medical assessment rather than assuming the cause is anxiety or matcha.
Evidence map: what is established, preliminary, and still uncertain
Established evidence
Caffeine is a central nervous system stimulant whose ordinary-dose actions are principally mediated by adenosine-receptor antagonism. Caffeine can increase anxiety and jitter-type symptoms in a dose-dependent way on average, while personal sensitivity varies substantially. Matcha contains a meaningful but variable caffeine dose.
Preliminary evidence
Small matcha trials suggest possible effects on stress-related anxiety, attention, and some aspects of mood under specific conditions. These findings are worth studying, but they are product-specific and do not establish treatment efficacy for anxiety disorders.
Limited or contested claims
The claim that matcha is inherently “calming,” that L-theanine neutralizes caffeine, that ceremonial matcha cannot cause jitters, or that matcha is categorically better than coffee for anxiety is not established. These statements collapse dose, individual response, product composition, expectation, and beverage context into a single marketing narrative.
Frequently asked questions
Does matcha cause anxiety?
It can contribute to anxious feelings in some people because it contains caffeine. The likelihood depends on dose, sensitivity, habitual caffeine use, sleep, other stimulant sources, and individual context. Matcha does not cause anxiety in everyone.
Why does matcha make me jittery?
The most likely explanation is that the caffeine dose exceeds your comfortable range under those conditions. A larger powder dose, another caffeine source, poor sleep, stress, or a change in caffeine sensitivity can all shift the experience.
Can matcha trigger a panic attack?
Caffeine can provoke panic at high doses in vulnerable people, particularly in panic disorder, but the classic challenge studies often used 400 to 750 mg of caffeine — much more than many ordinary matcha servings. Individual reactions can still occur at lower doses.
Is matcha better than coffee for anxiety?
Sometimes it may feel better, especially if the matcha serving contains less caffeine than the person’s usual coffee. There is limited direct evidence that matcha is intrinsically less anxiety-provoking than coffee when caffeine dose and other factors are matched.
Does L-theanine stop caffeine jitters?
Current evidence does not show that L-theanine reliably prevents caffeine-induced jitters or anxiety. Research on isolated L-theanine and L-theanine plus caffeine cannot be assumed to describe every matcha beverage.
How much caffeine is in matcha?
It varies. In one analysis of commercial matcha products, caffeine concentrations were roughly 17.7 to 35.0 mg per gram, which would correspond to about 35 to 70 mg in 2 g of those products. Café recipes and powder amounts can be higher or lower.
Can matcha help anxiety?
Matcha-specific evidence is preliminary. A small study found lower stress-related anxiety with one particular matcha formulation, but matcha has not been established as a treatment for anxiety disorders.
Why did matcha suddenly start making me anxious?
The matcha may have changed, the serving may be larger, your total caffeine intake may be higher, or your response may have shifted because of sleep, stress, smoking status, hormonal factors, medications, or other health changes that affect caffeine handling. Persistent new symptoms deserve medical assessment.
Can I drink matcha if I have an anxiety disorder?
There is no universal rule. Some people tolerate modest caffeine doses; others find that caffeine reliably worsens symptoms. Your own repeatable response and clinical context matter more than a blanket recommendation.
Should I stop matcha if it makes me jittery?
You do not necessarily need an all-or-nothing rule. A smaller measured serving, less frequent use, earlier timing, or avoiding other caffeine on the same day may be enough. If symptoms remain unpleasant, avoiding caffeinated matcha is a reasonable personal choice.
Related Articles
References
Baba, Y., Takihara, T., & Okamura, N. (2024). Matcha Does Not Affect Electroencephalography during Sleep but May Enhance Mental Well-Being: A Randomized Placebo-Controlled Clinical Trial. Nutrients, 16(17), 2907. https://pubmed.ncbi.nlm.nih.gov/39275223/
Dietz, C., Dekker, M., & Piqueras-Fiszman, B. (2017). An intervention study on the effect of matcha tea, in drink and snack bar formats, on mood and cognitive performance. Food Research International, 99, 72–83. https://pubmed.ncbi.nlm.nih.gov/28784536/
European Food Safety Authority. (2015). Caffeine: safety of caffeine. https://www.efsa.europa.eu/en/topics/topic/caffeine
Fredholm, B. B. (1995). Adenosine, adenosine receptors and the actions of caffeine. Pharmacology & Toxicology, 76(2), 93–101. https://pubmed.ncbi.nlm.nih.gov/7746802/
Gardiner, C., Weakley, J., Burke, L. M., Roach, G. D., Sargent, C., Maniar, N., Townshend, A., & Halson, S. L. (2023). The effect of caffeine on subsequent sleep: A systematic review and meta-analysis. Sleep Medicine Reviews, 69, 101764. https://pubmed.ncbi.nlm.nih.gov/36870101/
Gerolymos, C., Saddier, E., Boyer, L., & Fond, G. (2026). Cognitive and affective effects of L-Theanine: a systematic review and meta-analysis of 31 randomized trials. Molecular Psychiatry. https://pubmed.ncbi.nlm.nih.gov/42410082/
Grzegorzewski, J., Bartsch, F., Köller, A., & König, M. (2022). Pharmacokinetics of Caffeine: A Systematic Analysis of Reported Data for Application in Metabolic Phenotyping and Liver Function Testing. Frontiers in Pharmacology, 12, 752826. https://pubmed.ncbi.nlm.nih.gov/35280254/
Hoppe, J. M., Björkstrand, J., Vegelius, J., Klevebrant, L., Gingnell, M., & Frick, A. (2025). Acute effects of 150 mg caffeine on subjective, physiological, and behavioral components of anxiety in panic disorder and healthy controls: A randomized placebo-controlled crossover trial. Journal of Psychopharmacology, 39(8), 836–846. https://pubmed.ncbi.nlm.nih.gov/40577029/
Klevebrant, L., & Frick, A. (2022). Effects of caffeine on anxiety and panic attacks in patients with panic disorder: A systematic review and meta-analysis. General Hospital Psychiatry, 74, 22–31. https://pubmed.ncbi.nlm.nih.gov/34871964/
Liu, C., Wang, L., Zhang, C., Hu, Z., Tang, J., Xue, J., & Lu, W. (2024). Caffeine intake and anxiety: a meta-analysis. Frontiers in Psychology, 15, 1270246. https://pubmed.ncbi.nlm.nih.gov/38362247/
Lotshaw, S. C., Bradley, J. R., & Brooks, L. R. (1996). Illustrating caffeine’s pharmacological and expectancy effects utilizing a balanced placebo design. Journal of Drug Education, 26(1), 13–24. https://pubmed.ncbi.nlm.nih.gov/8991966/
Meyer, B. R., White, H. M., McCormack, J. D., & Niemeyer, E. D. (2023). Catechin Composition, Phenolic Content, and Antioxidant Properties of Commercially-Available Bagged, Gunpowder, and Matcha Green Teas. Plant Foods for Human Nutrition, 78(4), 662–669. https://pubmed.ncbi.nlm.nih.gov/37923855/
Nascimento, A. O. do, Silva, C. E. C. da, Silva, M. L. da, & Cunha, K. da C. (2026). The Effects of Caffeine on Anxiety Behavior in Healthy Individuals: A Systematic Review of the Literature. Stress and Health, 42(1), e70139. https://pubmed.ncbi.nlm.nih.gov/41549915/
Nehlig, A. (2018). Interindividual Differences in Caffeine Metabolism and Factors Driving Caffeine Consumption. Pharmacological Reviews, 70(2), 384–411. https://pubmed.ncbi.nlm.nih.gov/29514871/
Payne, E. R., Aceves-Martins, M., Dubost, J., Greyling, A., & de Roos, B. (2025). Effects of Tea (Camellia sinensis) or its Bioactive Compounds L-Theanine or L-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrition Reviews, 83(10), 1873–1891. https://pubmed.ncbi.nlm.nih.gov/40314930/
U.S. Food and Drug Administration. (2024). Spilling the Beans: How Much Caffeine is Too Much? https://www.fda.gov/consumers/consumer-updates/spilling-beans-how-much-caffeine-too-much
Uchida, K., Meno, K., Korenaga, T., et al. (2024). Effect of matcha green tea on cognitive functions and sleep quality in older adults with cognitive decline: A randomized controlled study over 12 months. PLoS One, 19(8), e0309287. https://pubmed.ncbi.nlm.nih.gov/39213264/
Unno, K., Furushima, D., Hamamoto, S., Iguchi, K., Yamada, H., Morita, A., Horie, H., & Nakamura, Y. (2018). Stress-Reducing Function of Matcha Green Tea in Animal Experiments and Clinical Trials. Nutrients, 10(10), 1468. https://pubmed.ncbi.nlm.nih.gov/30308973/
